SCHOTT Vitryxx® Product Description

Chemically, bioactive glass is an amorphous structure (like all glasses) that consists solely of elements found in the body - silicon, calcium, sodium, phosphorous and oxygen. Decades of research and studies have demonstrated that bioactive glasses are highly biocompatible. For cosmetics and cosmeceutical products, the unique biocompatibility of bioactive glasses translates to absolute skin compatibility, as has been demonstrated repeatedly in several long- and short-term human skin patch tests.

When activated with water, bioactive glass releases the ions of its composition as they possess a high bioavailability. These form a mineral matrix on the particle surface equivalent to that of natural hydroxy apatite.

Due to the mineral and inorganic character of SCHOTT Vitryxx^® bioactive glass, this class of anti-aging ingredient is insensitive to light and temperature extremes.

Bioactive Glass Applications

SCHOTT Vitryxx^® is an excellent anti-aging ingredient for cosmeceutical products (such as skincare and post-procedure care) as well as microdermabrasion purposes.

As of today, a broad range of cosmeceutical products have been successfully formulated with SCHOTT Vitryxx®. These include:

• Color Cosmetics (e.g. Mascara, Foundation, Eye Shadow, Lipsticks, Pressed Powder Blush)
• Skin Care (e.g. Facial Cream, Skin Gel), Hair Care (e.g. Conditioner, Styling Gel)
• Nail Care (e.g. Nail Enamel, Base Coat)
• Men’s Care (e.g. Shave Cream, After Shave Balm)
• Deodorants (e.g. Stick, Spray)
• Bath/Cleaning (e.g. Bar Soap, Liquid Soap)

SCHOTT Vitryxx® Bioactive Glass Technology

In an aqueous environment a rapid ion exchange between the sodium ion of the bioactive glass matrix and the hydrogen ion from the water takes place. This exchange generally leads to an increase in the pH of the surrounding solution, which can be substantial for finely grained bioactive glass powders having high surface to volume ratios.

The fast release of sodium ions is accompanied by a somewhat slower release of other species like calcium ions, silica and phosphorous. These releases are caused by a very slow dissolution of the glass surface. Under certain conditions in solution, these species will precipitate onto the glass surface and other nearby surfaces, to form calcium and phosphorous containing layers. These surface layers can transform into crystalline hydroxycarbonate apatite (HCA) – the chemical and structural equivalent of bone material. The ability of bioactive glass to build such a surface is the reason for the bonding ability to human tissue and can be seen as a measure of the “bioactivity” of the glass.

SCHOTT Vitryxx® Features / Specifications

Appearance:
SCHOTT Vitryxx® Bioactive Glass is a fine white powder that is odorless and tasteless. Due to its hydrophilic properties it must be stored dry.

Grain Sizes:
SCHOTT offers Vitryxx® Bioactive Glass in the following standard grain size. Customized grain sizes are also available upon request.

SM4.0 specified by d50: (4.0 ± 1.0) μm d95: ≤ 20 μm

Microbiological Properties:
Maximum content of microorganisms:

• Total viable count ≤ 100 cfu/g
• Yeasts and molds ≤ 100 cfu/g

Forms of Supply and Product Packaging

SCHOTT Vitryxx^® is currently available in two forms.

Vitryxx^®

• Material number: MD01
• Classification: Glass
• Form of delivery: Powder, grain sizes upon request
• INCI-name: Calcium Sodium Phosphosilicate
• CAS 65997-17-3
• EINECS 266046-0
• Mass % 100 % (Mica)

Vitryxx^® Bioactive Glass is suitable for waxy, solid, powder and highly viscous formulations.

Vitryxx^®M Bioactive Glass/Mica

• Material number: G018-270
• Classification: Glass/Mica
• Form of delivery: Powder, grain sizes upon request
• INCI-name: Calcium Sodium Phosphosilicate/Mica
• CAS 65997-17-3 (Vitryxx®)
• CAS 12001-26-2 (Mica)
• EINECS 266046-0 (Vitryxx®)
• EINECS 310-127-6 (Mica)
• Mass % 97-99% (Vitryxx®)
• Mass % 1-9 % (Mica)

Vitryxx^®M Bioactive Glass with Mica:
Pre-blending of SCHOTT Vitryxx® with Mica improves its dispersibility and enhances the appearance of the formulation. It is ideal for formulations like emulsions, liquids and low-viscous formulations.

Quality Assurance

For more information, please refer to our quality assurance processes or the product information below.